Researchers are using biophysical modeling and simulations on Jülich supercomputers to develop new brain tissue imaging methods. “When generating a detailed network model of the brain, nerve fiber crossings pose a major challenge for current neuroimaging techniques. Scientists at Forschungszentrum Jülich have now found that scattered light can be used to resolve the brain’s substructure like the crossing angles of the nerve fibers with micrometer resolution. For their studies, the researchers combined microscopy measurements and simulations on supercomputers.”